Publications

March 2021

Tauc HM, Rodriguez-Fernandez IA, Hackney JA, Pawlak M, Ronnen Oron T, Korzelius J, Moussa HF, Chaudhuri S, Modrusan Z, Edgar BA, Jasper H. Age-related changes in polycomb gene regulation disrupt lineage fidelity in intestinal stem cells. Elife. 2021 Mar 16;10. doi: 10.7554/eLife.62250. PubMed PMID: 33724181; PubMed Central PMCID: PMC7984841.

scRNAseq_figure.PNG

September 2020

Rodriguez-Fernandez IA, Tauc HM, Jasper H. Hallmarks of aging Drosophila intestinal stem cells. Mech Ageing Dev. 2020 Sep;190:111285. doi: 10.1016/j.mad.2020.111285. Epub 2020 Jun 13. PubMed PMID: 32544407.

old_ISC review.PNG

September 2019

Korzelius J, Azami S, Ronnen-Oron T, Koch P, Baldauf M, Meier E, Rodriguez-Fernandez IA, Groth M, Sousa-Victor P, Jasper H. The WT1-like transcription factor Klumpfuss maintains lineage commitment of enterocyte progenitors in the Drosophila intestine. Nat Commun. 2019 Sep 11;10(1):4123. doi: 10.1038/s41467-019-12003-0. PubMed PMID: 31511511; PubMed Central PMCID: PMC6739418.

Klu_FISH_image.PNG

June 2019

Wang L, Davis SS, Borch Jensen M, Rodriguez-Fernandez IA, Apaydin C, Juhasz G, Gibson BW, Schilling B, Ramanathan A, Ghaemmaghami S, Jasper H. JNK modifies neuronal metabolism to promote proteostasis and longevity. Aging Cell. 2019 Jun;18(3):e12849. doi: 10.1111/acel.12849. Epub 2019 Feb 27. PubMed PMID: 30810280; PubMed Central PMCID: PMC6516429.

Brain image_Wang paper.PNG

March 2019

Rodriguez-Fernandez IA, Qi Y, Jasper H. Loss of a proteostatic checkpoint in intestinal stem cells contributes to age-related epithelial dysfunction. Nat Commun. 2019 Mar 5;10(1):1050. doi: 10.1038/s41467-019-08982-9. PubMed PMID: 30837466; PubMed Central PMCID: PMC6401111.

ISC_Aggregates_4panels.PNG

November 2015

Rodriguez-Fernandez IA, Dell'Angelica EC. Identification of Atg2 and ArfGAP1 as Candidate Genetic Modifiers of the Eye Pigmentation Phenotype of Adaptor Protein-3 (AP-3) Mutants in Drosophila melanogaster. PLoS One. 2015;10(11):e0143026. doi: 10.1371/journal.pone.0143026.eCollection 2015. PubMed PMID: 26565960; PubMed Central PMCID: PMC4643998.

drosophila eyes_PlosOne paper 4panels.PNG

May 2012

Arboleda VA, Lee H, Parnaik R, Fleming A, Banerjee A, Ferraz-de-Souza B, Délot EC, Rodriguez-Fernandez IA, Braslavsky D, Bergadá I, Dell'Angelica EC, Nelson SF, Martinez-Agosto JA, Achermann JC, Vilain E. Mutations in the PCNA-binding domain of CDKN1C cause IMAGe syndrome. Nat Genet. 2012 May 27;44(7):788-92. doi: 10.1038/ng.2275. PubMed PMID: 22634751; PubMed Central PMCID: PMC3386373.

Arboleda image.PNG

April 2011

Hoyle DJ, Rodriguez-Fernandez IA, Dell'angelica EC. Functional interactions between OCA2 and the protein complexes BLOC-1, BLOC-2, and AP-3 inferred from epistatic analyses of mouse coat pigmentation. Pigment Cell Melanoma Res. 2011 Apr;24(2):275-81. doi: 10.1111/j.1755-148X.2010.00815.x. Epub 2010 Dec 17. PubMed PMID: 21392365; PubMed Central PMCID: PMC3070960

Mouse Hair_pic from paper.PNG

September 2010

Beck JR, Rodriguez-Fernandez IA, de Leon JC, Huynh MH, Carruthers VB, Morrissette NS, Bradley PJ. A novel family of Toxoplasma IMC proteins displays a hierarchical organization and functions in coordinating parasite division. PLoS Pathog. 2010 Sep 9;6(9):e1001094. doi: 10.1371/journal.ppat.1001094. PubMed PMID: 20844581; PubMed Central PMCID: PMC2936552.

Toxoplasma_Beck.PNG

February 2010

Ghiani CA, Starcevic M, Rodriguez-Fernandez IA, Nazarian R, Cheli VT, Chan LN, Malvar JS, de Vellis J, Sabatti C, Dell'Angelica EC. The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth. Mol Psychiatry. 2010 Feb;15(2):115, 204-15. doi: 10.1038/mp.2009.58. Epub 2009 Jun 23. PubMed PMID: 19546860; PubMed Central PMCID: PMC2811213.

Cypin_CristinaGianni.PNG

April 2009

Rodriguez-Fernandez IA, Dell'Angelica EC. A data-mining approach to rank candidate protein-binding partners-The case of biogenesis of lysosome-related organelles complex-1 (BLOC-1). J Inherit Metab Dis. 2009 Apr;32(2):190-203. doi: 10.1007/s10545-008-1014-7. Epub 2008 Dec 12. PubMed PMID: 19083121; PubMed Central PMCID: PMC2756288.

Datamining approach_pic.PNG
 

NCBI myBibliography

For a complete list of published work go to: NCBI myBibliography